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Review of Pharmacology In 10 minutes

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SAADEK
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تاريخ التسجيل : 29/11/2007
نقاط : 4239

Review of Pharmacology In 10 minutes

مُساهمة من طرف SAADEK في الأربعاء أكتوبر 06 2010, 14:33


بسم الله الرحمن الرحيم

تعالى نراجع الفارما في 10 دقايق

اقرا كدة وحاول تحفظ عشان تربط الأمور ببعضها

وأنا كمان هحاول معاك


Beta blockers: members

"The NEPAL Prime Minister":

Timolol

Nadolol

Esmolol

Pindolol

Atenolol

Labetalol

Propranolol

Metoprolol


Beta-blockers: main contraindications, cautions

ABCDE:

Asthma

Block (heart block)

COPD

Diabetes mellitus

Electrolyte (hyperkalemia)


Beta-blockers: nonselective beta-blockers

"Tim Pinches His Nasal Problem" (because he has a runny nose...):

Timolol

Pindolol

Hismolol

Naldolol

Propranolol

pinch معناها قرص.. يعني قرص مناخيره عشان كان عنده برد.. دة معنى الجملة


Beta-blockers: side effects

"BBC Loses Viewers In Rochedale":

Bradycardia

Bronchoconstriction

Claudication

Lipids

Vivid dreams & nightmares

-ve Inotropic action
Reduced sensitivity to hypoglycaemia


Ca++ channel blockers: uses

CA++ MASH:

Cerebral vasospasm/ CHF

Angina

Migranes

Atrial flutter, fibrillation

Supraventricular tachycardia

Hypertension

_ Alternatively: "CHASM":

Cererbral vasospasm / CHF

Hypertension

Angina

Suprventricular tachyarrhythmia

Migranes


Captopril (an ACE inhibitor): side effects

CAPTOPRIL:

Cough

Angioedema/ Agranulocystosis

Proteinuria/ Potassium excess

Taste changes

Orthostatic hypotension

Pregnancy contraindication/ Pancreatitis/ Pressure drop (first dose hypertension)

Renal failure (and renal artery stenosis contraindication)/ Rash

Indomethacin inhibition

Leukopenia/ Liver toxicity

Clopidogrel: use

CLOPIdogrel is a drug that prevents

CLots, an Oral Platelet Inhibitor (OPI).

Enoxaprin (prototype low molecular weight heparin): action, monitoring

EnoXaprin only acts on factor Xa.

Monitor Xa concentration, rather than APTT.

HMG-CoA reductase inhibitors (statins): side effects, contraindications, interactions

HMG-CoA:

_ Side effects:

Hepatotoxicity

Myositis [aka rhabdomyolysis]

_ Contraindications:

Girl during pregnancy/ Growing children

_ Interactions:

Coumarin/ Cyclosporine

Hypertension: treatment

ABCD:

ACE inhibitors/ AngII antagonists (sometimes Alpha agonists also)

Beta blockers

Calcium antagonists

Diuretics

Patent ductus arteriosus: treatment

"Come In and Close the door":
INdomethacin is used to Close PDA



Thrombolytic agents

USA:

Urokinase

Streptokinase

Alteplase (tPA)

Warfarin: action, monitoring

WePT:

Warfarin works on the extrinsic pathway and is monitored by PT.

Warfarin: metabolism

SLOW:

_ Has a slow onset of action.

_ A quicK Vitamin K antagonist, though.

Small lipid-soluble molecule

Liver: site of action

Oral route of administration.

Warfarin


Gynaecomastia-causing drugs

DISCOS:

Digoxin

Isoniazid

Spironolactone

Cimetidine

Oestrogens

Stilboestrol


K+ increasing agents

K-BANK:

K-sparing diuretic

Beta blocker

ACEI

NSAID

K supplement


Diuretics: thiazides: indications

"CHIC to use thiazides":

CHF

Hypertension

Insipidous
Calcium calculi


Osmotic diuretics: members

GUM:

Glycerol

Urea
Mannitol


Aspirin: side effects

ASPIRIN:

Asthma

Salicyalism

Peptic ulcer disease/ Phosphorylation-oxidation uncoupling/ PPH/ Platelet disaggregation/ Premature closure of PDA

Intestinal blood loss

Reye's syndrome

Idiosyncracy

Noise (tinnitus)

Atropine use: tachycardia or bradycardia

"A goes with B":
Atropine used clinically to treat Bradycardia


Beta 1 selective blockers

"BEAM ONE up, Scotty":

Beta 1 blockers:

Esmolol

Atenolol
Metropolol


Ipratropium: action
Atropine is buried in the middle: iprAtropium, so it behaves like Atropine



Methyldopa: side effects

METHYLDOPA:

Mental retardation

Electrolyte imbalance

Tolerance

Headache/ Hepatotoxicity

psYcological upset

Lactation in female

Dry mouth

Oedema

Parkinsonism
Anaemia (haemolytic)


Migraine: prophylaxis drugs

"Very Volatile Pharmacotherapeutic Agents For Migraine Prophylaxis":

Verpamil

Valproic acid

Pizotifen

Amitriptyline

Flunarizine

Methysergide
Propranolol


Myasthenia gravis: edrophonium vs. pyridostigmine

eDrophonium is for Diagnosis.

pyRIDostigmine is to get RID of symptoms.

Nicotinic effects

MTWTF (days of week):

Mydriasis/ Muscle cramps

Tachycardia

Weakness

Twitching

Hypertension/ Hyperglycemia

Fasiculation

Physostigmine vs. neostigmine

LMNOP:

Lipid soluble

Miotic

Natural

Orally absorbed well

Physostigmine

_ Neostigmine, on the contrary, is:

Water soluble

Used in myesthenia gravis

Synthetic

Poor oral absorption

Pupils in overdose: morphine vs. amphetamine

"MorPHINE: Fine. AmPHETamine: Fat":

Morphine overdose: pupils constricted (fine).

Amphetamine overdose: pupils dilated (fat).

Reserpine action [

Reserpine depletes the Reserves of catecholamines [and serotonin].

Metabolism enzyme inducers

"Randy's Black Car Goes Putt Putt and Smokes":

Rifampin

Barbiturates

Carbamazepine

Grisoefulvin

Phenytoin

Phenobarb

Smoking cigarettes

Zero order kinetics drugs (most common ones)

"PEAZ (sounds like pees) out a constant amount":

Phenytoin

Ethanol

Aspirin

Zero order

_ Someone that pees out a constant amount describes zero order kinetics (always the same amount out)

Asthma drugs: leukotriene inhibitor action

zAfirlukast: Antagonist of lipoxygenase

zIlueton: Inhibitor of LT receptor

Beta-1 vs Beta-2 receptor location

"You have 1 heart and 2 lungs":

Beta-1 are therefore primarily on heart.

Beta-2 primarily on lungs.

Antirheumatic agents (disease modifying): members

CHAMP:

Cyclophosphamide

Hydroxycloroquine and choloroquinine

Auranofin and other gold compounds

Methotrexate

Penicillamine


منقول





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DR:MIDO
المدير العام
المدير العام

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تاريخ التسجيل : 25/11/2007
نقاط : 10273

رد: Review of Pharmacology In 10 minutes

مُساهمة من طرف DR:MIDO في الأربعاء أكتوبر 06 2010, 14:59

تسلم الأيادى يا مان كلام جميل

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محب الحبيب
فارس جديد
فارس جديد

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تاريخ التسجيل : 25/02/2010
نقاط : 2838

رد: Review of Pharmacology In 10 minutes

مُساهمة من طرف محب الحبيب في الخميس أكتوبر 07 2010, 19:35

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